Taube Koret Center

Recent papers from Taube Koret Center

1. Survey of the human proteostasis network: the ubiquitin-proteasome systemAutophagy · 2026
2. Survey of the human proteostasis network: translation, protein folding, and organelle-specific systemsAutophagy · 2026
3. Survey of the human proteostasis network: the autophagy-lysosome pathwayAutophagy · 2026
4. Lifespan single-cell transcriptomic atlas of the human prefrontal cortexNature · 2026
5. Single-cell atlas of transcriptomic vulnerability across brain disordersNature · 2026
6. Single-nucleus transcriptome-wide association study of human brain disordersNature · 2026
7. AI-based characterization of Alzheimer’s disease phenotypes from population-scale single-cell dataNature Medicine · 2026
8. Personalized single-cell transcriptomics reveals molecular diversity in Alzheimer’s diseaseNature Communications · 2026
9. Single-nucleus atlas of cell-type specific genetic regulation in the human brainNature Genetics · 2026
10. Autism mutations rewire protein interaction networks to drive neurodevelopmental pathologyScience · 2026
11. Survey of the human proteostasis network: the ubiquitin-proteasome system2026
12. Wild-type C9orf72 expression is a genetic modifier of C9-ALS survival2026
13. TDP-43 loss induces cryptic polyadenylation in ALS/FTDNature Neuroscience · 2025
14. Intersecting impact of CAG repeat and Huntingtin knockout in stem cell-derived cortical neurons2025
15. Rare variant analyses validate known ALS genes in a multi-ethnic population and identifies ANTXR2 as a candidate in PLSBMC Genomics · 2024
16. A dynamic in vitro model of Down syndrome neurogenesis with trisomy 21 gene dosage correctionScience Advances · 2024
17. Disease related changes in ATAC-seq of iPSC-derived motor neuron lines from ALS patients and controlsNature Communications · 2024
18. A Trisomy 21-linked Hematopoietic Gene Variant in Microglia Confers Resilience in Human iPSC Models of Alzheimer’s Disease2024
19. A foundational atlas of autism protein interactions reveals molecular convergence2023
20. Disease related changes in ATAC-Seq of more than 450 iPSC-derived motor neuron lines from ALS patients and controls2023