Cassava Sciences (United States)

Recent papers from Cassava Sciences (United States)

1. A conserved vdcBCD cluster encoding a vanillate/p-hydroxybenzoate decarboxylase catalyzes the formation of phenol from p-hydroxybenzoate in the cork-associated Streptomyces graminifolii B37 strainFrontiers in Microbiology · 2026
2. Inhaled LTI-03 for idiopathic pulmonary fibrosis: a randomized dose escalation studyNature Communications · 2026
3. The LTI-01-2001 phase 2a trial of intrapleural LTI-01 in patients with infected, non-draining pleural effusionsRespiratory Research · 2026
4. Comparing Medicare Claims in Patients with Lumbar Discogenic Pain Managed Conservatively or with Intradiscal Nucleus Pulposus AllograftJournal of Pain Research · 2026
5. Methane intensity and emissions across major oil and gas basins and individual jurisdictions using MethaneSAT observationsAtmospheric chemistry and physics · 2026
6. Phase 3 randomized clinical trials of simufilam in mild-to-moderate Alzheimer’s diseaseThe Journal of Prevention of Alzheimer s Disease · 2026
7. A Primer on Anatomy, Biophysics, Pathology, Imaging and Treatment of the Intervertebral Disc and the Anterior Spinal Column: The Discogenic, Intervertebral, Spinal Column (DISC) ASPN WorkgroupJournal of Pain Research · 2025
8. Anti-CV2/CRMP5 autoantibodies as drivers of sensory neuron excitability and pain in ratsNature Communications · 2025
9. Identification of sensory fiber types in mouse temporomandibular joint tissuesScientific Reports · 2025
10. Innervation of Retrodiscal Tissues in Patients with Temporomandibular Joint Disorder2025
11. Leptin-Upregulated Metastasis-Associated Protein 1 Promotes Vasculogenic Mimicry in Breast Cancer CellsInternational Journal of Molecular Sciences · 2025
12. Beyond single targets: leveraging degeneracy in sodium channels for osteoarthritis analgesiaPAIN Reports · 2025
13. Collapsin Response Mediator Protein 2 (CRMP2) Modulates Mitochondrial Oxidative Metabolism in Knock-In AD Mouse ModelCells · 2025
14. Investigating Mechanically Activated Currents from Trigeminal Neurons of Nonhuman PrimateseNeuro · 2025
15. Truncated TrkB: The predominant TrkB Isoform in Nociceptors2024
16. Methane point source quantification using MethaneAIR: a new airborne imaging spectrometerSHILAP Revista de lepidopterología · 2023
17. Simufilam Reverses Aberrant Receptor Interactions of Filamin A in Alzheimer’s DiseaseInternational Journal of Molecular Sciences · 2023
18. Simufilam suppresses overactive mTOR and restores its sensitivity to insulin in Alzheimer’s disease patient lymphocytesFrontiers in Aging · 2023
19. Targeting α7 nicotinic acetylcholine receptors and their protein interactions in Alzheimer's disease drug developmentDrug Development Research · 2023
20. Filamin A inhibition reduces seizure activity in a mouse model of focal cortical malformationsScience Translational Medicine · 2020