Nkarta Therapeutics (United States)

Recent papers from Nkarta Therapeutics (United States)

1. Key considerations for advancing chimeric antigen receptor (CAR) T-cell therapy for systemic lupus erythematosus (SLE): a multi-partner/disciplinary working group perspectiveRMD Open · 2025
2. Characterization of AB598, a CD39 Enzymatic Inhibitory Antibody for the Treatment of Solid TumorsMolecular Cancer Therapeutics · 2024
3. Abstract 3603: NKX101, an allogeneic off-the-shelf CAR NK cell therapy targeting NKG2D-Ls, has potent anti-leukemic activity alone or in combination with Ara-CCancer Research · 2024
4. Abstract 3604: NKX101, an allogeneic off-the-shelf NKG2D CAR-NK cell therapy, has potent in vitro cytotoxicity against patient-derived AML leukemic stem cells and non-leukemic stem cell blastsCancer Research · 2024
5. First in human data of NKX019, an allogeneic CAR NK for the treatment of relapsed/refractory (R/R) B‐cell malignanciesHematological Oncology · 2023
6. Targeting CD73 with AB680 (Quemliclustat), a Novel and Potent Small-Molecule CD73 Inhibitor, Restores Immune Functionality and Facilitates Antitumor ImmunityMolecular Cancer Therapeutics · 2022
7. Accelerating Socket Repair via WNT3A Curtails Alveolar Ridge ResorptionJournal of Dental Research · 2021
8. Kv1.1 channels regulate early postnatal neurogenesis in mouse hippocampus via the TrkB signaling pathwayeLife · 2021
9. Bronchus-associated macrophages efficiently capture and present soluble inhaled antigens and are capable of local Th2 cell activation2020
10. TLR7 trafficking and signaling in B cells is regulated by the MHCII-associated invariant chainJournal of Cell Science · 2020
11. cAMP-Fyn signaling in the dorsomedial striatum direct pathway drives excessive alcohol use2020
12. Biomechanics of Immediate Postextraction Implant OsseointegrationJournal of Dental Research · 2018
13. Wnt-Responsive Odontoblasts Secrete New Dentin after Superficial Tooth InjuryJournal of Dental Research · 2018
14. A Wnt-Responsive PDL Population Effectuates Extraction Socket HealingJournal of Dental Research · 2018
15. 3D: diversity, dynamics, differential testing – a proposed pipeline for analysis of next-generation sequencing T cell repertoire dataBMC Bioinformatics · 2017
16. Antifibrotic Effects of the Dual CCR2/CCR5 Antagonist Cenicriviroc in Animal Models of Liver and Kidney FibrosisPLoS ONE · 2016
17. Chemokine (C‐C motif) receptor 2–positive monocytes aggravate the early phase of acetaminophen‐induced acute liver injuryHepatology · 2016
18. Pharmacokinetics, Safety, and CCR2/CCR5 Antagonist Activity of Cenicriviroc in Participants With Mild or Moderate Hepatic ImpairmentClinical and Translational Science · 2016
19. Efficacy and safety study of cenicriviroc for the treatment of non-alcoholic steatohepatitis in adult subjects with liver fibrosis: CENTAUR Phase 2b study designContemporary Clinical Trials · 2016
20. Cenicriviroc, a Novel CCR5 (R5) and CCR2 Antagonist, Shows In Vitro Activity against R5 Tropic HIV-2 Clinical IsolatesPLoS ONE · 2015