Unity Biotechnology (United States)

Recent papers from Unity Biotechnology (United States)

1. Safety and Efficacy of Senolytic UBX1325 in Diabetic Macular EdemaNEJM Evidence · 2025
2. Multifocal Electroretinography Changes after UBX1325 (Foselutoclax) Treatment in Neovascular Age-Related Macular DegenerationJournal of Clinical Medicine · 2024
3. Online Search and Optimal Product Rankings: An Empirical FrameworkMarketing Science · 2023
4. Integration of transcriptomes of senescent cell models with multi-tissue patient samples reveals reduced COL6A3 as an inducer of senescenceCell Reports · 2023
5. Longevity factor klotho enhances cognition in aged nonhuman primatesNature Aging · 2023
6. Obesity triggers tumoral senescence and renders poorly immunogenic malignancies amenable to senolysisProceedings of the National Academy of Sciences · 2022
7. Technology readiness levels for machine learning systemsNature Communications · 2022
8. Neural Fields in Visual Computing and BeyondComputer Graphics Forum · 2022
9. KL1 Domain of Longevity Factor Klotho Mimics the Metabolome of Cognitive Stimulation and Enhances Cognition in Young and Aging MiceJournal of Neuroscience · 2022
10. Improved therapeutic index of an acidic pH-selective antibodymAbs · 2022
11. Caspase‐8 Variant G Regulates Rheumatoid Arthritis Fibroblast‐Like Synoviocyte Aggressive BehaviorACR Open Rheumatology · 2021
12. Leveraging historical data to optimize the number of covariates and their explained variance in the analysis of randomized clinical trials.Statistical Methods in Medical Research · 2021
13. p21 produces a bioactive secretome that places stressed cells under immunosurveillanceScience · 2021
14. Cdkn1a transcript variant 2 is a marker of aging and cellular senescenceAging · 2021
15. Rova-T enhances the anti-tumor activity of anti-PD1 in a murine model of small cell lung cancer with endogenous Dll3 expressionTranslational Oncology · 2020
16. Concurrent Binary Trees (with application to longest edge bisection)Proceedings of the ACM on Computer Graphics and Interactive Techniques · 2020
17. Synovial cell cross-talk with cartilage plays a major role in the pathogenesis of osteoarthritisScientific Reports · 2020
18. Enhancer Activity Requires CBP/P300 Bromodomain-Dependent Histone H3K27 AcetylationCell Reports · 2018
19. Oxidation resistance 1 is a novel senolytic targetAging Cell · 2018
20. Senescent cells and osteoarthritis: a painful connectionJournal of Clinical Investigation · 2018