HemoShear (United States)

Recent papers from HemoShear (United States)

1. Break-induced replication drives large-scale genomic amplifications in cancer cells2024
2. Parenteral platforms for tunable, long-acting administration of a highly hydrophobic antiretroviral drugScientific Reports · 2024
3. Human cardiovascular disease model predicts xanthine oxidase inhibitor cardiovascular riskPLoS ONE · 2023
4. Neuropsychological endpoints for clinical trials in methylmalonic acidemia and propionic acidemia: A pilot studyMolecular Genetics and Metabolism Reports · 2023
5. Genomic and biochemical analysis of repeatedly observed variants in DBT in individuals with maple syrup urine disease of Central American ancestryAmerican Journal of Medical Genetics Part A · 2022
6. Genome-wide CRISPR Screening to Identify Drivers of TGF-β-Induced Liver Fibrosis in Human Hepatic Stellate CellsACS Chemical Biology · 2022
7. Identification of 2,2-Dimethylbutanoic Acid (HST5040), a Clinical Development Candidate for the Treatment of Propionic Acidemia and Methylmalonic AcidemiaJournal of Medicinal Chemistry · 2021
8. A novel small molecule approach for the treatment of propionic and methylmalonic acidemiasMolecular Genetics and Metabolism · 2021
9. Validation of a multicellular tumor microenvironment system for modeling patient tumor biology and drug responseScientific Reports · 2021
10. Ketohexokinase inhibition improves NASH by reducing fructose-induced steatosis and fibrogenesisJHEP Reports · 2020
11. Biochemical and anaplerotic applications of in vitro models of propionic acidemia and methylmalonic acidemia using patient-derived primary hepatocytesMolecular Genetics and Metabolism · 2020
12. Gene Expression Predicts Histological Severity and Reveals Distinct Molecular Profiles of Nonalcoholic Fatty Liver DiseaseScientific Reports · 2019
13. Non-alcoholic fatty liver disease (NAFLD) models in drug discoveryExpert Opinion on Drug Discovery · 2017
14. Exposure of Induced Pluripotent Stem Cell-Derived Vascular Endothelial and Smooth Muscle Cells in Coculture to Hemodynamics Induces Primary Vascular Cell-Like PhenotypesStem Cells Translational Medicine · 2017
15. Development of an in vitro human liver system for interrogating nonalcoholic steatohepatitisJCI Insight · 2016
16. Drug-induced steatohepatitisExpert Opinion on Drug Metabolism & Toxicology · 2016
17. Red Blood Cell Dysfunction Induced by High-Fat DietCirculation · 2015
18. Endovascular coil embolization of a spinal epidural arteriovenous fistula with associated cord compression from an enlarging venous varixInterventional Neuroradiology · 2015
19. Mechanisms of Amplified Arteriogenesis in Collateral Artery Segments Exposed to Reversed Flow DirectionArteriosclerosis Thrombosis and Vascular Biology · 2015
20. Hemodynamic flow improves rat hepatocyte morphology, function, and metabolic activity in vitroAJP Cell Physiology · 2013