Red Glead Discovery (Sweden)

Recent papers from Red Glead Discovery (Sweden)

1. Nonclinical characterization of ACP-204, a novel selective serotonin receptor subtype 2A receptor inverse agonistJournal of Pharmacology and Experimental Therapeutics · 2026
2. Synthesis and In Vitro Profiling of Psilocin Derivatives: Improved Stability and Synthetic PropertiesJournal of Medicinal Chemistry · 2025
3. Development and Characterization of a High-Affinity Selective Galectin-3 Mouse Tool Compound in Mouse Models of CancerJournal of Medicinal Chemistry · 2024
4. Structural basis of CDNF interaction with the UPR regulator GRP78Nature Communications · 2024
5. Galectin-8N-Selective 4-Halophenylphthalazinone-Galactals Double π-Stack in a Unique PocketACS Medicinal Chemistry Letters · 2024
6. Discovery of the Selective and Orally Available Galectin-1 Inhibitor GB1908 as a Potential Treatment for Lung CancerJournal of Medicinal Chemistry · 2024
7. N‐Butylpyrrolidinone is an equally good solvent as N,N‐dimethylformamide for microwave assisted solid phase peptide synthesisJournal of Peptide Science · 2024
8. Functional and structural impact of 10 ACADM missense mutations on human medium chain acyl-Coa dehydrogenaseBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2023
9. Probing the Allosteric Modulation of P-Glycoprotein: A Medicinal Chemistry Approach Toward the Identification of Noncompetitive P-Gp InhibitorsACS Omega · 2023
10. Long-range communication between transmembrane- and nucleotide-binding domains does not depend on drug binding to mutant P-glycoproteinJournal of Biomolecular Structure and Dynamics · 2023
11. A practical and environmentally friendly protocol for synthesis of α‐deuterated carboxylic acidsJournal of Labelled Compounds and Radiopharmaceuticals · 2023
12. Characterization of the Aquaporin-9 Inhibitor RG100204 In Vitro and in db/db MiceCells · 2022
13. Discovery and Optimization of the First Highly Effective and Orally Available Galectin-3 Inhibitors for Treatment of Fibrotic DiseaseJournal of Medicinal Chemistry · 2022
14. Probing the allosteric modulation of P-glycoprotein: A medicinal chemistry approach towards the identification of non-competitive P-gp inhibitors.2022
15. Long-range communication between transmembrane- and nucleotide-binding domains does not depend on drug binding to mutant P-glycoprotein2022
16. RG100204, A Novel Aquaporin-9 Inhibitor, Reduces Septic Cardiomyopathy and Multiple Organ Failure in Murine SepsisFrontiers in Immunology · 2022
17. Investigation of Carboxylic Acid Isosteres and Prodrugs for Inhibition of the Human SIRT5 Lysine Deacylase Enzyme**Angewandte Chemie · 2022
18. NUDT15-mediated hydrolysis limits the efficacy of anti-HCMV drug ganciclovirCell chemical biology · 2021
19. Molecular Dynamics Studies of Therapeutic Liquid Mixtures and Their Binding to MycobacteriaFrontiers in Pharmacology · 2021
20. Evolution of Nitrogen-Based Alkylating Anticancer AgentsProcesses · 2021