Biaffin (Germany)

Recent papers from Biaffin (Germany)

1. A PKA-selective inhibitor captures an open but more ordered conformation of the PKA catalytic subunitProceedings of the National Academy of Sciences · 2026
2. Divalent metal ions control activity and inhibition of protein kinasesMetallomics · 2017
3. Dynamic and flexible H3K9me3 bridging via HP1β dimerization establishes a plastic state of condensed chromatinNature Communications · 2016
4. Structural Insights into Cargo Recognition by the Yeast PTS1 ReceptorJournal of Biological Chemistry · 2015
5. Divalent Metal Ions Mg²⁺ and Ca²⁺ Have Distinct Effects on Protein Kinase A Activity and RegulationACS Chemical Biology · 2015
6. Characterization of the biological anti-staphylococcal functionality of hUK-66 IgG1, a humanized monoclonal antibody as substantial component for an immunotherapeutic approachHuman Vaccines & Immunotherapeutics · 2014
7. Structure of cyclin G-associated kinase (GAK) trapped in different conformations using nanobodiesBiochemical Journal · 2014
8. Phosphodiesterase-8A binds to and regulates Raf-1 kinaseProceedings of the National Academy of Sciences · 2013
9. Structural and functional analysis of phosphorylation-specific binders of the kinase ERK from designed ankyrin repeat protein librariesProceedings of the National Academy of Sciences · 2012
10. Methylation of Lysine 9 in Histone H3 Directs Alternative Modes of Highly Dynamic Interaction of Heterochromatin Protein hHP1β with the NucleosomeJournal of Biological Chemistry · 2012
11. Kinetics of the interaction between anti‐FVIII antibodies and FVIII from therapeutic concentrates, with and without von Willebrand factor, assessed by surface plasmon resonanceHaemophilia · 2012
12. The Pseudomonas aeruginosa Chemotaxis Methyltransferase CheR1 Impacts on Bacterial Surface SamplingPLoS ONE · 2011
13. Small Molecule AKAP-Protein Kinase A (PKA) Interaction Disruptors That Activate PKA Interfere with Compartmentalized cAMP Signaling in Cardiac MyocytesENLIGHTEN (Jurnal Bimbingan dan Konseling Islam) · 2010
14. RNAs actively cycle on the Sm-like protein HfqGenes & Development · 2010
15. Functional Antibodies Targeting IsaA of Staphylococcus aureus Augment Host Immune Response and Open New Perspectives for Antibacterial TherapyAntimicrobial Agents and Chemotherapy · 2010
16. Chemical tools selectively target components of the PKA systemBMC Chemical Biology · 2009
17. Systematic interpretation of cyclic nucleotide binding studies using KinetXBasePROTEOMICS · 2008
18. Plasma Protein Binding Properties to Immobilized Heparin and Heparin–Albumin ConjugateArtificial Organs · 2007
19. High-affinity AKAP7δ–protein kinase A interaction yields novel protein kinase A-anchoring disruptor peptidesENLIGHTEN (Jurnal Bimbingan dan Konseling Islam) · 2006
20. The cell wall subproteome of Listeria monocytogenesPROTEOMICS · 2004