Icon (United Kingdom)

Recent papers from Icon (United Kingdom)

1. Comparative effectiveness of cladribine tablets versus fingolimod in the treatment of highly active multiple sclerosis: A real-world studyMultiple Sclerosis and Related Disorders · 2023
2. Population Pharmacokinetics of Olanzapine and Samidorphan When Administered in Combination in Healthy Subjects and Patients With SchizophreniaThe Journal of Clinical Pharmacology · 2021
3. A Physiologically Based Pharmacokinetic Model to Predict Potential Drug–Drug Interactions and Inform Dosing of Acumapimod, an Oral p38 MAPK InhibitorCPT Pharmacometrics & Systems Pharmacology · 2020
4. Neutrophil-to-Lymphocyte Ratio as a Prognostic Factor of Disease-free Survival in Postnephrectomy High-risk Locoregional Renal Cell Carcinoma: Analysis of the S-TRAC TrialClinical Cancer Research · 2020
5. Phase III Trial of Adjuvant Sunitinib in Patients with High-Risk Renal Cell Carcinoma: Exploratory Pharmacogenomic AnalysisClinical Cancer Research · 2018
6. Population Pharmacokinetic Analysis and Model-Based Simulations of Aripiprazole for a 1-Day Initiation Regimen for the Long-Acting Antipsychotic Aripiprazole LauroxilEuropean Journal of Drug Metabolism and Pharmacokinetics · 2018
7. Brain Monitoring Devices in Neuroscience Clinical Research: The Potential of Remote Monitoring Using Sensors, Wearables, and Mobile DevicesClinical Pharmacology & Therapeutics · 2018
8. Oliceridine (TRV130), a Novel G Protein–Biased Ligand at the μ‐Opioid Receptor, Demonstrates a Predictable Relationship Between Plasma Concentrations and Pain Relief. I: Development of a Pharmacokinetic/Pharmacodynamic ModelThe Journal of Clinical Pharmacology · 2018
9. Oliceridine, a Novel G Protein–Biased Ligand at the μ‐Opioid Receptor, Demonstrates a Predictable Relationship Between Plasma Concentrations and Pain Relief. II: Simulation of Potential Phase 3 Study Designs Using a Pharmacokinetic/Pharmacodynamic ModelThe Journal of Clinical Pharmacology · 2018
10. Standards for Instrument Migration When Implementing Paper Patient-Reported Outcome Instruments Electronically: Recommendations from a Qualitative Synthesis of Cognitive Interview and Usability StudiesValue in Health · 2017
11. Pharmacokinetic Profile of a 2-Month Dose Regimen of Aripiprazole Lauroxil: A Phase I Study and a Population Pharmacokinetic ModelCNS Drugs · 2017
12. Safety and Pharmacokinetics of Bendamustine Rapid‐Infusion FormulationThe Journal of Clinical Pharmacology · 2017
13. Estimands: discussion points from the PSI estimands and sensitivity expert groupPharmaceutical Statistics · 2016
14. Population pharmacokinetics of dolutegravir in HIV‐infected treatment‐naive patientsBritish Journal of Clinical Pharmacology · 2015
15. The hidden burden of adult allergic rhinitis: UK healthcare resource utilisation surveyClinical and Translational Allergy · 2015
16. Multiplicity: discussion points from the Statisticians in the Pharmaceutical Industry multiplicity expert groupPharmaceutical Statistics · 2013
17. Inpatient rehabilitation in multiple sclerosisNeurology · 1999