Supplementary Figure 1 from Pharmacologic Inhibition of SIRT1 Limits the Growth of Tumoral and Metastatic Granulosa Cells by Affecting mTOR, Myc, and E2F Pathways

Key Points

• Inhibition of SIRT1 effectively limits the growth of tumoral and metastatic granulosa cells.
• The study highlights the role of mTOR, Myc, and E2F pathways in tumor growth regulation.
• Methods involved assessing SIRT1 expression and its effects on cellular growth mechanisms.
• This research could lead to new targeted therapies for controlling tumor growth based on SIRT1 pathways.