Supplementary Figure S2 from Molecular Characterization of Residual Muscle-Invasive Bladder Cancer Identifies a Scar-Like Transcriptomic Profile with Favorable Prognosis after Neoadjuvant Therapy

Key Points

• Identifying a scar-like transcriptomic profile indicates favorable prognosis after therapy.
• High signature scores in gene expressions like TGF-beta and FGFR3 correlate with positive outcomes.
• Utilizing gene expression profiling, biological clusters were defined from cystectomy samples treated with atezolizumab.
• Findings emphasize the role of angiogenesis and apoptosis pathways in bladder cancer recovery.