Biphasic Progression of Radiation-Induced Carotid Stenosis: The Predictive Role of Low-Density Plaque

Key Points

• This research aims to examine the role of low-density plaque in predicting the progression of radiation-induced carotid stenosis.
• Identified low-density plaque as a predictor of accelerated radiation-induced carotid stenosis (RICS).
• Proposed a biphasic model with slow progression before LDP detection and rapid progression afterward.
• Recommended annual CT scans for intensified surveillance in high-risk patients.
• Demonstrated low-density plaque is a critical predictor of RICS progression.
• Found no significant association between calcification and RICS progression.
• Supported the need for timely interventions to prevent occlusion.