Combining Serum Pharmacochemistry and Metabolomics to Characterize the Synergistic Compatibility Principle of Polygonati Rhizoma and Angelicae Sinensis Radix for MAFLD Mitigation. | Synapse
January 25, 2026
Combining Serum Pharmacochemistry and Metabolomics to Characterize the Synergistic Compatibility Principle of Polygonati Rhizoma and Angelicae Sinensis Radix for MAFLD Mitigation.
Key Points
The aim is to explore how the combination of two herbs impacts MAFLD mitigation by identifying their synergistic effects.
Utilized serum pharmacochemistry and metabolomics to analyze herbal components.
Investigated targets and pathways related to MAFLD.
Evaluated the synergistic effects of Polygonati Rhizoma and Angelicae Sinensis Radix.
Identified multiple components and targets associated with the combined herbal treatment.
Demonstrated potential mechanisms of synergism that may contribute to MAFLD mitigation.
Found that JHP had broader effects compared to either herb alone.
Abstract
Our study found that JHP was associated with more components, targets, and pathways, which may be the mechanisms of JHP synergism.