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February 16, 2026European journal of medical research6 citationsOpen Access

Efficacy and safety of trabeculectomy versus micro-invasive glaucoma procedures (MIGPs) in managing glaucoma: a systematic review and meta-analysis

KCKai-Yang ChenHCHoi-Chun ChanCCChi-Ming Chan

Key Points

  • This research aims to compare the efficacy and safety of trabeculectomy and micro-invasive glaucoma procedures (MIGPs) in managing glaucoma.
  • Conducted a systematic review and meta-analysis of existing studies
  • Compared intraocular pressure (IOP) outcomes of trabeculectomy and MIGPs
  • Evaluated postoperative medication requirements and safety profiles
  • Trabeculectomy resulted in greater IOP reduction compared to MIGPs
  • MIGPs had a more favorable safety profile with fewer complications
  • Higher rates of complete success observed in trabeculectomy, but lower rates of qualified success

Abstract

Trabeculectomy provides greater IOP reduction, whereas MIGPs demonstrate a more favorable safety profile and reduced postoperative medication burden, with mixed effects on success definitions (higher complete success but lower qualified success). These findings support individualized surgical selection based on target IOP, risk tolerance, and patient-centered priorities.

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Cite This Study

Chen et al. (2026) studied this question.

synapsesocial.com/papers/6992b4469b75e639e9b092abhttps://doi.org/10.1186/s40001-026-03868-1
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