What question did this study set out to answer?

This research aims to compare the efficacy and safety of trabeculectomy and micro-invasive glaucoma procedures (MIGPs) in managing glaucoma.

February 16, 2026Open Access

Efficacy and safety of trabeculectomy versus micro-invasive glaucoma procedures (MIGPs) in managing glaucoma: a systematic review and meta-analysis

Key Points

This research aims to compare the efficacy and safety of trabeculectomy and micro-invasive glaucoma procedures (MIGPs) in managing glaucoma.
Conducted a systematic review and meta-analysis of existing studies
Compared intraocular pressure (IOP) outcomes of trabeculectomy and MIGPs
Evaluated postoperative medication requirements and safety profiles
Trabeculectomy resulted in greater IOP reduction compared to MIGPs
MIGPs had a more favorable safety profile with fewer complications
Higher rates of complete success observed in trabeculectomy, but lower rates of qualified success

Abstract

Trabeculectomy provides greater IOP reduction, whereas MIGPs demonstrate a more favorable safety profile and reduced postoperative medication burden, with mixed effects on success definitions (higher complete success but lower qualified success). These findings support individualized surgical selection based on target IOP, risk tolerance, and patient-centered priorities.

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Cite This Study

Chen et al. (Fri,) studied this question.

synapsesocial.com/papers/6992b4469b75e639e9b092ab https://doi.org/https://doi.org/10.1186/s40001-026-03868-1

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