Lay Summary Clinical trials are essential to improving treatment and survival for children with brain and spinal tumors. However, nearly 90% of these trials happen in high-income countries, while most affected children live in low- and middle-income countries, where trials are scarce. These trials also tend to be smaller and focus more on supportive care. Expanding global trial access is critical to developing treatments that work for all children, improving care standards, and building lasting research capacity. Greater international collaboration can help address these gaps and ensure advances benefit children everywhere.
Mikkelsen et al. (Mon,) studied this question.