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Investigate the distribution and characteristics of clinical trials for children with CNS tumors across different income countries.

February 26, 2026Neuro-Oncology Pediatrics

Global Analysis of Clinical Trials for Children and Adolescents with CNS Tumors

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Investigate the distribution and characteristics of clinical trials for children with CNS tumors across different income countries.
Reviewed clinical trial data focused on children with CNS tumors.
Analyzed the prevalence of trials in high-income versus low- and middle-income countries.
Examined trial size and focus areas, particularly supportive care.
Approximately 90% of trials occur in high-income countries.
Trials in low- and middle-income countries are fewer and generally smaller.
A significant emphasis on supportive care rather than curative treatments was noted.

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Analysis highlights disparities in clinical trials for CNS tumors in children, suggesting the need for global access improvements.

Mikkelsen et al. (2026) studied this question.

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