Prevalence and Risk Factors of Elevated Alanine Aminotransferase (ALT) in 2382 Treatment-naïve HBV/HDV Co-Infected Patients.

Key Points

• This research aims to identify the prevalence and risk factors of elevated ALT levels in treatment-naïve HBV/HDV co-infected patients.
• Analyzed ALT levels in a cohort of treatment-naïve patients co-infected with HBV and HDV
• Compared inflammatory processes between chronic hepatitis D and chronic hepatitis B
• Evaluated the association of ALT levels with liver cirrhosis
• Demonstrated that chronic hepatitis D shows an earlier and more severe inflammatory response than chronic hepatitis B
• Identified significant prevalence of elevated ALT levels in the cohort
• Called for longitudinal studies to enhance risk stratification for therapy prioritization