March 3, 2026Open Access

Electroacupuncture alleviates depression and gastrointestinal dysfunction by rebalancing GABAergic activity in the central amygdala

Depressive-like symptoms and gastric deficits significantly reduced in CUMS mice following electroacupuncture treatment.
Key evidence includes the involvement of CeA GABAergic neurons in mediating these benefits on behavior.
Assessment using electroacupuncture techniques demonstrated rebalancing of GABAergic activity in the central amygdala.
These findings support the potential for electroacupuncture as a therapeutic intervention for related disorders.

EA attenuates depressive-like and gastric deficits in CUMS mice, with evidence implicating CeA GABAergic neurons as a contributory node.

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