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March 3, 2026World Journal of PsychiatryOpen Access

Electroacupuncture alleviates depression and gastrointestinal dysfunction by rebalancing GABAergic activity in the central amygdala

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Authors

HMHongkun MaSZShan-Lan ZhuXLXueyan Li

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Overview

Observational analysis shows improvement in depression and gastrointestinal deficits in CUMS mice, suggesting neurochemical benefits.

Key Points

  • Depressive-like symptoms and gastric deficits significantly reduced in CUMS mice following electroacupuncture treatment.
  • Key evidence includes the involvement of CeA GABAergic neurons in mediating these benefits on behavior.
  • Assessment using electroacupuncture techniques demonstrated rebalancing of GABAergic activity in the central amygdala.
  • These findings support the potential for electroacupuncture as a therapeutic intervention for related disorders.

Cite This Study

Ma et al. (2026) studied this question.

synapsesocial.com/papers/69a75d88c6e9836116a27abfhttps://doi.org/10.5498/wjp.v16.i2.114736
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