Small cavitand macrocycles from direct C-C coupling of s-aryltetrazine units

Key Points

• The research aims to synthesize macrocyclic structures from s-aryltetrazine subunits using carbon–carbon bond formation.
• Utilized Ullmann homocoupling for bond formation
• Assembled tri- and tetramer structures
• Created macrocycles with compact, rigid geometries
• Successfully synthesized small cavitand macrocycles
• Generated structures with small internal cavities
• Demonstrated the feasibility of using bromophenyltetrazines