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Evolution of mpox virus in Peru: case B.1.6.1 | Synapse

March 12, 2026

Evolution of mpox virus in Peru: case B.1.6.1

Key Points

This research aims to identify and characterize a new lineage of the mpox virus in Peru.
Identification of the mpox virus lineage B.1.6.1
Characterization of five specific mutations
Observation of cases primarily in immunocompromised young and adult men
Emergence of lineage B.1.6.1 identified in Peru
Characterized by five mutations: Q81stop, A21T, E34K, S65L, M424I, and S1590F
Lineage predominantly observed in immunocompromised individuals

Abstract

Here, we report the emergence of a new mpox lineage, named B.1.6.1. This lineage is native to Peru and has been reported mainly in young and adult men with immunocompromised systems. It is characterized by 5 mutations: OPG019 (Q81stop), OPG025 (A21T, E34K), OPG121 (S65L), OPG064 (M424I) and OPG210 (S1590F).

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Cite This Study

Lizarraga et al. (Mon,) studied this question.

synapsesocial.com/papers/69b25aab96eeacc4fcec8a09 https://doi.org/https://doi.org/10.1080/20477724.2026.2638838