Evolution of mpox virus in Peru: case B.1.6.1

Wendy Lizarraga; Verónica Hurtado; Víctor Jimenez‐Vasquez; Iris S. Molina; Nieves Sevilla; Luis Barcena; Priscila Lope‐Pari; Lucia Rojas; Johanna Balbuena; Carlos Padilla‐Rojas

doi:10.1080/20477724.2026.2638838

March 9, 2026Pathogens and Global Health

Evolution of mpox virus in Peru: case B.1.6.1

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Key Points

This research aims to identify and characterize a new lineage of the mpox virus in Peru.
Identification of the mpox virus lineage B.1.6.1
Characterization of five specific mutations
Observation of cases primarily in immunocompromised young and adult men
Emergence of lineage B.1.6.1 identified in Peru
Characterized by five mutations: Q81stop, A21T, E34K, S65L, M424I, and S1590F
Lineage predominantly observed in immunocompromised individuals

Implication

Case report unveils a new mpox lineage with specific mutations in immunocompromised men, suggesting evolutionary patterns.

Abstract

Here, we report the emergence of a new mpox lineage, named B.1.6.1. This lineage is native to Peru and has been reported mainly in young and adult men with immunocompromised systems. It is characterized by 5 mutations: OPG019 (Q81stop), OPG025 (A21T, E34K), OPG121 (S65L), OPG064 (M424I) and OPG210 (S1590F).

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Cite This Study

Lizarraga et al. (2026) studied this question.

synapsesocial.com/papers/69b25aab96eeacc4fcec8a09 https://doi.org/10.1080/20477724.2026.2638838

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Evolution of mpox virus in Peru: case B.1.6.1

Key Points

Implication

Abstract

Discussion

Cite This Study

Evolution of mpox virus in Peru: case B.1.6.1

Key Points

Implication

Abstract

Discussion

Cite This Study

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