Efficacy of leukocyte-platelet-rich fibrin (L-PRF) and injectable platelet-rich fibrin (i-PRF) on the rate of canine retraction: a split mouth, randomized controlled trial

Key Points

• This research aims to compare the efficacy of leukocyte-platelet-rich fibrin and injectable platelet-rich fibrin on canine retraction rates.
• Conducted a split-mouth, randomized controlled trial
• Evaluated effects of L-PRF and submucosal i-PRF
• Measured canine retraction over 5 months
• Assessed safety regarding anchorage loss and root resorption.
• L-PRF and i-PRF accelerated canine retraction in the early phase
• Greater total movement observed at 5 months
• Intraligamental i-PRF showed no significant effect
• All PRF methods were safe with no increased anchorage loss or root resorption.