Randomized controlled trial shows L-PRF and i-PRF accelerate canine retraction, suggesting effective orthodontic interventions.
L-PRF and submucosal i-PRF significantly accelerated canine retraction in the early phase, with greater total movement at 5 months. Intraligamental i-PRF showed no significant effect. All PRF methods were safe, with no increase in anchorage loss or root resorption.
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Kamrani et al. (2026) studied this question.
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