What question did this study set out to answer?

To analyze a rare case of conjunctival amyloidosis that resembled Parinaud's syndrome.

April 4, 2026Open Access

Primary conjunctival amyloidosis mimicking Parinaud's syndrome

Key Points

To analyze a rare case of conjunctival amyloidosis that resembled Parinaud's syndrome.
Case report of a 60-year-old female
Observation of a unilateral lesion in the inferior bulbar conjunctiva
Description of lesion characteristics including size and color
Lesion presented as extensive nodular mass
Poorly defined borders noted
Clinical presentation mimicked symptoms of Parinaud's syndrome

Abstract

Amyloidosis is characterized by the extracellular deposition of amyloid protein fibrils in tissues, including the conjunctiva, due to their insolubility in proteolytic enzymes. Conjunctival amyloidosis, particularly involving the eyelid conjunctiva, is a rare clinical entity. We report the case of a 60-year-old Caucasian female who presented with a unilateral lesion in the inferior bulbar conjunctiva, extending to the entire inferior tarsal region and fornix. The lesion appeared as an extensive, elevated, pinkish-yellowish nodular mass with poorly defined borders. An ...

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