Primary conjunctival amyloidosis mimicking Parinaud's syndrome

Amyloidosis is characterized by the extracellular deposition of amyloid protein fibrils in tissues, including the conjunctiva, due to their insolubility in proteolytic enzymes. Conjunctival amyloidosis, particularly involving the eyelid conjunctiva, is a rare clinical entity. We report the case of a 60-year-old Caucasian female who presented with a unilateral lesion in the inferior bulbar conjunctiva, extending to the entire inferior tarsal region and fornix. The lesion appeared as an extensive, elevated, pinkish-yellowish nodular mass with poorly defined borders. An ...