How do left atrial morphology, size, and function compare between patients with transthyretin cardiac amyloidosis, primary hypertrophic cardiomyopathy, and controls?
Left atrial reservoir and pump function are more severely impaired in transthyretin cardiac amyloidosis than in hypertrophic cardiomyopathy, independent of LA volume and LVEF, suggesting a more altered LA wall structure.
LA reservoir and pump function were significantly impaired in both TTR-CA and HCM patients compared with controls, but mainly in the former group, irrespective of LA volume and LV ejection fraction, likely caused by a more altered LA wall structure. (Circ J 2016; 80: 1830-1837).
Gregorio et al. (Fri,) studied this question.
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