This work describes a practical method for coupling chloropyridazines and aryl/hetero aryl amines to get substituted aryl/hetroarylaminopyridazines. The newly developed condition tolerates a wide range of functional groups, including various heterocycles, electron withdrawing/donating groups, and sensitive functional groups. This approach offers a convenient route to a range of secondary heterocyclic aminopyridazines that were otherwise challenging to synthesize.
Nimje et al. (Tue,) studied this question.