Does atrial fibrillation increase the risk of death in subjects from the Framingham Heart Study?
Atrial fibrillation is independently associated with a significant increase in mortality risk across both sexes and a wide range of ages.
In subjects from the original cohort of the Framingham Heart Study, AF was associated with a 1.5- to 1.9-fold mortality risk after adjustment for the preexisting cardiovascular conditions with which AF was related. The decreased survival seen with AF was present in men and women and across a wide range of ages.
Benjamin et al. (Tue,) studied this question.