July 8, 2017Open Access
View Full PaperAge- and sex-specific analysis of patients with embolic stroke of undetermined source
Structured PICO
Does age or sex predict stroke recurrence and death in patients with embolic stroke of undetermined source?
P
Population
Patients with embolic stroke of undetermined source (ESUS)
O
Outcome
Stroke recurrence and deathhard clinical
Age is a strong predictor of stroke recurrence and mortality in ESUS, highlighting that age distribution in clinical trials may significantly influence their statistical power.
Abstract
Age, but not sex, is a strong predictor of stroke recurrence and death in ESUS. The risk is ≈3- and 8-fold higher in patients >80 years compared with those <60 years of age, respectively. The age distribution in the ongoing ESUS trials may potentially influence their power to detect a significant treatment association.
Cite This Study
Ntaios et al. (Sat,) studied this question.