Does early treatment with enalapril prevent the development of late cardiotoxicity in high-risk patients treated with high-dose chemotherapy?
Early initiation of enalapril in patients receiving high-dose chemotherapy who develop elevated troponin I may prevent subsequent cardiotoxicity.
In high-risk, HDC-treated patients, defined by an increased troponin I value, early treatment with enalapril seems to prevent the development of late cardiotoxicity.
Cardinale et al. (Tue,) studied this question.