Do peak CK-MB and peak troponin I levels prognosticate in-hospital mortality in patients with acute myocardial infarction?
Peak CK-MB provides slightly higher incremental prognostic value for in-hospital mortality than peak troponin I in patients with acute myocardial infarction.
Both peak CK-MB and peak troponin I levels are independently associated with in-hospital mortality in this large contemporary database of AMI patients treated in routine practice. Peak marker values slightly improved model performance in prognosticating in-hospital mortality; the incremental value was higher with CK-MB than with troponin I. These findings may help to guide future risk stratification algorithms and contribute to more efficient use of serial cardiac marker measurements in clinical practice.
Chin et al. (Tue,) studied this question.