December 20, 2001
The FHA domain
Key Points
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Abstract
The forkhead-associated (FHA) domain is a small protein module recently shown to recognize phosphothreonine epitopes on proteins. It is present in a diverse range of proteins in eukaryotic cells, such as kinases, phosphatases, kinesins, transcription factors, RNA-binding proteins, and metabolic enzymes. It is also found in a number of bacterial proteins. This suggests that FHA domain-mediated phospho-dependent assembly of protein complexes is an ancient and widespread regulatory mechanism.
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Cite this study
Durocher et al. (Thu,) studied this question.
synapsesocial.com/papers/69fe07877f24f003e8271fce — DOI: https://doi.org/10.1016/s0014-5793(01)03294-x
Authors
D
Daniel Durocher
Mount Sinai Hospital
Stephen P. Jackson
Université Paris-Sud
Journals
FEBS Letters
Actions
Institutions
University of Cambridge
University of Toronto
Mount Sinai Hospital
References and Citations
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