The elusive endo-product of the archetypal Diels-Alder reaction of furan and maleic anhydride – observed in the solid state at last | Synapse
May 15, 2026Open Access
The elusive endo-product of the archetypal Diels-Alder reaction of furan and maleic anhydride – observed in the solid state at last
Key Points
This research aims to elucidate the elusive endo-product of the Diels-Alder reaction between furan and maleic anhydride.
Utilized solid-state analysis technique to observe the endo-product.
Performed Diels-Alder reaction using furan and maleic anhydride.
Assessed the results through various chemical characterization methods.
The endo-product was successfully observed in the solid state, highlighting its stability.
Demonstrated deviations from the Alder endo-rule, indicating unique reactivity patterns.
Provided structural insights that could enhance understanding of Diels-Alder mechanisms.
Abstract
The 4+2 reaction of furan and maleic anhydride is an archetypal, textbook example of Diels-Alder reactivity, whose role as an early and prominent exception from the Alder endo-rule has made...