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February 24, 2009The American Journal of Gastroenterology

Guidelines for Prevention of NSAID-Related Ulcer Complications

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Population

Patients at risk of NSAID-related upper gastrointestinal injury

Design

Guideline

Key result

The American College of Gastroenterology developed guidelines for the prevention of NSAID-related upper gastrointestinal injury, addressing COX-2 inhibitors, traditional NSAIDs, and H. pylori.

Authors

FLFrank L. LanzaFCFrancis K.L. ChanEQEamonn M.M. Quigley

Discussion

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Overview

Informs NSAID gastroprotection decisions now; extends prior consensus on COX-2 inhibitors, traditional NSAIDs, and H. pylori.

Structured PICO

P
Population
Patients at risk of NSAID-related upper gastrointestinal injury
I
Intervention
Prevention strategies for NSAID-related ulcer complications (including COX-2 inhibitors and management of interactions with aspirin and H. pylori)
O
Outcome
Prevention of upper gastrointestinal injury

Provides expert consensus and evidence-based guidelines from the American College of Gastroenterology for preventing NSAID-related upper gastrointestinal injury.

Cite This Study

Lanza et al. (2009) conducted a review in NSAID-Related Ulcer Complications. Guidelines for prevention of NSAID-related ulcer complications was evaluated. The American College of Gastroenterology developed guidelines for the prevention of NSAID-related upper gastrointestinal injury, addressing COX-2 inhibitors, traditional NSAIDs, and H. pylori.

synapsesocial.com/papers/6a0f3a7214089a5783bde195https://doi.org/10.1038/ajg.2009.115
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Guidelines for Prevention of NSAID-Related Ulcer Complications2009 · 94 citations
  2. 2A guideline for the treatment and prevention of NSAID-induced ulcers1998 · 279 citations
  3. 3Guidelines for the appropriate use of non‐steroidal anti‐inflammatory drugs, cyclo‐oxygenase‐2‐specific inhibitors and proton pump inhibitors in patients requiring chronic anti‐inflammatory therapy2004 · 123 citations
  4. 4Canadian consensus guidelines on long‐term nonsteroidal anti‐inflammatory drug therapy and the need for gastroprotection: benefits versus risks2008 · 160 citations
  5. 5Risk of Upper Gastrointestinal Injury and Events in Patients Treated With Cyclooxygenase (COX)-1/COX-2 Nonsteroidal Antiinflammatory Drugs (NSAIDs), COX-2 Selective NSAIDs, and Gastroprotective Cotherapy2004 · 50 citations