What type of study is this?

This is a Quantitative Study study.

September 17, 2025

Multiparametric functional MRI of the kidneys in healthy subjects before and after water intake.

Key Points

Functional MRI parameters can change significantly after water intake, indicating renal response.
Specific MRI techniques like ASL and BOLD were employed to capture renal function variations.
Ten healthy volunteers were scanned to assess how hydration affects various renal MRI metrics.
Findings suggest multiparametric MRI could improve kidney imaging by reflecting hydration impacts.

Abstract

Motivation: Multiparameter MR metrics are sensitive to fluid transport in the kidney induced by diuretic challenges 1. However, widely accepted reference values remain limited, and the impact of hydration status on specific MRI parameters is not yet fully understood. Goal(s): Evaluation of functional MRI parameters of the kidneys throughout the day in the healthy renal cortex and medulla before and after water intake. Approach: Ten volunteers underwent two MRI examinations on the same day. The multiparametric MRI protocol includes ASL, IVIM, BOLD, MT, T1 and T2 mapping. Results: Changes observed in certain MRI parameters may reflect parenchymal alterations in healthy kidneys after hydration. Impact: Our study showed that the multiparametric functional MRI of the kidneys can help evaluate the renal function depending on its hydration status and may play an important role in kidney imaging.

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Cite This Study

Chaika et al. (Tue,) studied this question.

synapsesocial.com/papers/68d4596631b076d99fa5c1a5 https://doi.org/https://doi.org/10.58530/2025/3034

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