Pd21-09 Health-Related Quality of Life in Patients Undergoing Ileal Ureter Replacement for Extensive Ureteral Stricture: A Multi-Institutional Prospective Study

You have accessJournal of UrologyReconstruction: Augmentation, Substitution, Diversion (PD21)1 May 2024PD21-09 HEALTH-RELATED QUALITY OF LIFE IN PATIENTS UNDERGOING ILEAL URETER REPLACEMENT FOR EXTENSIVE URETERAL STRICTURE: A MULTI-INSTITUTIONAL PROSPECTIVE STUDY Xiang Wang, Derun Li, Guanpeng Han, Kunlin Yang, Hua Guan, Zhihua Li, Liqun Zhou, Kai Zhang, and Xuesong Li Xiang WangXiang Wang , Derun LiDerun Li , Guanpeng HanGuanpeng Han , Kunlin YangKunlin Yang , Hua GuanHua Guan , Zhihua LiZhihua Li , Liqun ZhouLiqun Zhou , Kai ZhangKai Zhang , and Xuesong LiXuesong Li View All Author Informationhttps://doi.org/10.1097/01.JU.0001008888.07102.14.09AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Ileal ureter replacement (IUR) is a valuable procedure for ureteral reconstruction. However, its impact on patients' HRQoL remains elusive. This study aimed to longitudinally compare the HRQoL during the first year following IUR and identified prognostic factors predicting HRQoL improvement. METHODS: We prospectively conducted a multi-center study with patients underwent IUR for extensive ureteral stricture (US) between April 2020 and July 2022. Patients were invited to self-complete the Short Form 36 Health Survey Questionnaire to evaluate HRQoL before surgery, 6-mo and 12-mo postoperatively. A significant improvement in HRQoL was considered as the follow-up scores that improved by more than 10 points compared with baseline scores. RESULTS: Overall, 82 consecutive patients were included. The mean age was 44.6 years with 52 (63.4%) being female. Although patients with US presented significantly poor baseline HRQoL, there was a remarkable improvement following IUR. Specifically, both the 6-mo and 12-mo postoperative scores were significantly improved compared with baseline in all domains. Moreover, 45.5-79.2% of patients achieved significant improvement in different domains within 12 months postoperatively. Furthermore, some patients' characteristics (gender, age, body mass index, live area, education status, presenting symptom, surgical approach, anxiety and depression level, etc) were prognostic factors for significant improvement in HRQoL postoperatively. CONCLUSIONS: Patients underwent IUR reported profound improvement in HRQoL within 12 months. Certain patient features and clinical variables predicted significant improvement in HRQoL postoperatively. These satisfactory outcomes provided by IUR further support it as a valuable procedure for complex ureteral reconstruction. Download PPTDownload PPT Source of Funding: This study was supported by grants from the National High Level Hospital Clinical Research Funding (Scientific Research Seed Fund of Peking University First Hospital) (2022SF78) © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e457 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Xiang Wang More articles by this author Derun Li More articles by this author Guanpeng Han More articles by this author Kunlin Yang More articles by this author Hua Guan More articles by this author Zhihua Li More articles by this author Liqun Zhou More articles by this author Kai Zhang More articles by this author Xuesong Li More articles by this author Expand All Advertisement PDF downloadLoading ...