March 18, 2024Open Access

Impaired Relaxation in Induced Pluripotent Stem Cell‐Derived Cardiomyocytes with Pathogenic TNNI3 Mutation of Pediatric Restrictive Cardiomyopathy

RWRenjie WangTianjin University of Traditional Chinese Medicine MHMoyu HasegawaYamagata University HSHidehiro SuginobeMuseum of Japanese Art Yamato Bunkakan

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Abstract

Restrictive cardiomyopathy (RCM) is characterized by impaired diastolic function with preserved ventricular contraction. Several pathogenic variants in sarcomere genes, including

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