A heteroatom of difference: investigation of thiazolidine- and oxazolidine-4-carboxylates as hydrolytically cleavable profragrances

Key Points

• The research aims to explore heterocyclic profragrances for controlled release of fragrances in laundry care.
• Synthesis of thiazolidine and oxazolidine carboxylates from amino acids
• Testing fragrance release through hydrolysis under acidic and alkaline conditions
• Comparative analysis of fragrance delivery efficiency during hydrolysis
• Profragrances showed effective release of aldehydes and ketones
• Hydrolysis rates varied significantly between acidic and alkaline environments
• Thiazolidine derivatives demonstrated superior performance in fragrance stability