Development and validation of prognostic nomograms based on peripheral blood T-cell counts and their dynamic changes for patients with nasopharyngeal carcinoma receiving radiotherapy

Key Points

• The study aims to develop and validate prognostic nomograms using peripheral blood T-cell counts for nasopharyngeal carcinoma patients receiving radiotherapy.
• Developed nomograms based on T-cell counts and their dynamic changes.
• Validated the nomograms in an external cohort.
• Compared prognostic accuracy with conventional staging systems.
• Nomograms reliably predicted progression-free survival (PFS) and overall survival (OS).
• Improved prognostic discrimination beyond traditional staging methods.