What question did this study set out to answer?

The research aims to investigate the relationship between bacterial diversity and type 2 diabetes mellitus (T2DM) in the context of periodontitis.

February 28, 2026Open Access

Integrative Analysis of Bacterial Diversity in Patients with Type 2 Diabetes Mellitus and Periodontitis Using a Case-Control Microbiome Approach

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Key Points

The research aims to investigate the relationship between bacterial diversity and type 2 diabetes mellitus (T2DM) in the context of periodontitis.
Conducted a case-control microbiome analysis.
Analyzed salivary samples from patients with T2DM and periodontitis.
Identified bacterial taxa and functional pathways.
Detected significant shifts in salivary microbial composition in T2DM patients.
Linked specific taxa to the presence of periodontitis.
Predicted functional pathways associated with altered microbial diversity.

Abstract

T2DM is associated with distinct shifts in salivary microbial composition and predicted function, revealing taxa and pathways linked to periodontitis.

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Discussion

Cite this study

Martínez-Gregorio et al. (Thu,) studied this question.

synapsesocial.com/papers/69a286da0a974eb0d3c021a4 — DOI: https://doi.org/10.1093/jambio/lxag051

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Authors

Héctor Martínez-Gregorio

Autonomous University of Tlaxcala

Fernando Vallejo-Lecuona

Autonomous University of Tlaxcala

Fernando Ambriz-Barrera

Autonomous University of Tlaxcala

Journals

Journal of Applied Microbiology

Actions

Institutions

Dana-Farber Cancer Institute

National Institute of Genomic Medicine

Autonomous University of Tlaxcala

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Integrative Analysis of Bacterial Diversity in Patients with Type 2 Diabetes Mellitus and Periodontitis Using a Case-Control Microbiome Approach

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Cite this study

Also consider

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

Also consider