3D ECM-Inflammation Model on a Microfluidic Chip for Neutrophil Transmigration from Whole Blood Investigations

Key Points

• The aim is to examine how neutrophils behave during inflammation in a controlled environment using a microfluidic chip.
• Developed a 3D ECM inflammation model on a microfluidic chip.
• Utilized whole blood to study neutrophil behavior.
• Monitored neutrophil transmigration in response to inflammation.
• Demonstrated effective neutrophil transmigration across the chip.
• Highlighted key cellular responses relevant to inflammation.
• Provided insights into the dynamics of neutrophil behavior in inflammatory conditions.