March 3, 2026Physics and Imaging in Radiation Oncology0 citationsOpen Access

The impact of bladder and rectal dynamics on prostate and seminal vesicles intrafraction motion and deformation in radiotherapy

FLFebrio LunardoAustralian e-Health Research Centre ATAlex Y. TanElectrophysiology LBLaura BakerTownsville Hospital

Key Points

Prostate and seminal vesicle intrafraction motion is influenced by bladder volume at treatment start, indicating a predictive relationship.
A baseline bladder volume of 190 mL correlates with reduced motion and deformation in treatment target areas.
Assessment of bladder and rectal dynamics reveals potential for decreased treatment margins, enhancing precision in radiotherapy.
Findings may lead to protocol alterations aiming for optimal bladder volume during radiotherapy sessions.

Abstract

This study demonstrated that the baseline bladder volume at start of a treatment fraction predicts for both SV and prostate intrafraction motion, by mediating the effect of bladder filling, and that SV treatment margins could be reduced for a favourably sized bladder. These findings may support refining treatment protocols such as aiming for an initial bladder volume of at least 190 mL.

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