Development of a non-genetic risk prediction model for allopurinol-induced severe cutaneous adverse drug reactions: a multicenter retrospective observational study

Key Points

• Severe cutaneous adverse drug reactions were effectively predicted using a new model.
• The model highlights three key risk factors in a diverse multicenter dataset.
• This retrospective observational study assesses historical patient data across multiple clinics.
• Findings underscore the need for better screening tools to manage drug reactions.