June 18, 2002Open Access
View Full PaperMental Stress Induces Prolonged Endothelial Dysfunction via Endothelin-A Receptors
Structured PICO
Does selective endothelin-A receptor antagonism prevent prolonged endothelial dysfunction induced by mental stress?
I
Intervention
Selective endothelin-A receptor antagonism
O
Outcome
Prolonged endothelial dysfunctionsurrogate
Selective endothelin-A receptor antagonism prevents mental stress-induced prolonged endothelial dysfunction, providing a novel link to atherosclerotic vascular disease.
Abstract
Mental stress induces prolonged endothelial dysfunction, which is prevented by selective endothelin-A receptor antagonism. This represents a novel and important link between mental stress and atherosclerotic vascular disease.