In this issue of Blood, Nishimura et al 1 demonstrate that expression of NUTM1 fusion genes in hematopoietic progenitors can induce a "one-hit leukemia" by driving differentiation to highly proliferating, stem-like B-cell progenitors.
Shiloh et al. (Thu,) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: