The visible-light-driven, organophotoredox-catalyzed vinyl group transfer reaction is described. The strategic use of proaromatic, bench-stable, and readily prepared 4-vinyl-dihydropyridine (DHP) derivatives triggers the vinyl group transfer that can couple stereoselectively with fluorinated esters and amides to forge the C(sp3)-C(sp2) bond. The obtained products are transformed into diverse fluorinated scaffolds. Preliminary mechanistic investigations are outlined.
Mandhotra et al. (Fri,) studied this question.