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April 4, 2026Open Access

HFpEF prevalence among individuals with type 2 diabetes mellitus in a primary care setting: A matter of definitions (Early-HFpEF cohort profile)

Key Points

This research aims to explore the differences in HFpEF prevalence among individuals with type 2 diabetes based on varying diagnostic algorithms.
Comparison of four different algorithms for HFpEF prevalence assessment.
Evaluation of ESC and NHG guidelines specifically in primary care settings.
Analysis of sensitivity and discrimination levels of the guidelines.
High prevalence of HFpEF identified by the ESC guideline, suggesting poor discrimination.
NHG guideline exhibited low sensitivity in detecting cases.
ESC algorithm with higher E/e' threshold may be more suitable for individuals with type 2 diabetes.

Abstract

Discrepancies in HFpEF prevalence were observed across the four algorithms. The ESC-guideline identified a high prevalence, suggesting low discrimination, while the NHG guideline showed low sensitivity. The ESC algorithm with a higher E/e' threshold may be most appropriate for this population.

HFpEF prevalence among individuals with type 2 diabetes mellitus in a primary care setting: A matter of definitions (Early-HFpEF cohort profile)

Key Points

Abstract

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