HFpEF prevalence among individuals with type 2 diabetes mellitus in a primary care setting: A matter of definitions (Early-HFpEF cohort profile)

M.J.C. van den Berg; R. Meer; A. Uijl; A.G. Hoek; KA Kortekaas; E. Wierda; M. Hollander; P.J.M. Elders; M.T. Blom; J.W.J. Beulens

doi:10.1016/j.pcd.2026.03.009

April 1, 2026Primary care diabetesOpen Access

HFpEF prevalence among individuals with type 2 diabetes mellitus in a primary care setting: A matter of definitions (Early-HFpEF cohort profile)

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Key Points

This research aims to explore the differences in HFpEF prevalence among individuals with type 2 diabetes based on varying diagnostic algorithms.
Comparison of four different algorithms for HFpEF prevalence assessment.
Evaluation of ESC and NHG guidelines specifically in primary care settings.
Analysis of sensitivity and discrimination levels of the guidelines.
High prevalence of HFpEF identified by the ESC guideline, suggesting poor discrimination.
NHG guideline exhibited low sensitivity in detecting cases.
ESC algorithm with higher E/e' threshold may be more suitable for individuals with type 2 diabetes.

Implication

Assessment of HFpEF prevalence in type 2 diabetes using different algorithms highlights significant discrepancies.

Abstract

Discrepancies in HFpEF prevalence were observed across the four algorithms. The ESC-guideline identified a high prevalence, suggesting low discrimination, while the NHG guideline showed low sensitivity. The ESC algorithm with a higher E/e' threshold may be most appropriate for this population.

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Cite This Study

Berg et al. (2026) studied this question.

synapsesocial.com/papers/69d0ae68659487ece0fa4641 https://doi.org/10.1016/j.pcd.2026.03.009

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HFpEF prevalence among individuals with type 2 diabetes mellitus in a primary care setting: A matter of definitions (Early-HFpEF cohort profile)

Key Points

Implication

Abstract

Discussion

Cite This Study

HFpEF prevalence among individuals with type 2 diabetes mellitus in a primary care setting: A matter of definitions (Early-HFpEF cohort profile)

Key Points

Implication

Abstract

Discussion

Cite This Study

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