Heterozygous knockout of Cx43 does not alter ventricular conduction velocities or ECG parameters in mice.
A sensitive method that accurately measures local CVs throughout the ventricles revealed no changes in Cx43+/- mice, which is consistent with the demonstration that ECG parameter values in the heterozygous mice are the same as those in wild-type mice.
Morley et al. (Fri,) studied this question.